美迪西请说为您解说GLP-1 蛋白激酶激动不已剂的成长。

胰高血糖素样肽-1（GLP-1）蛋白激酶激情剂的布置很多的改变症为2型高血压和肥胖症症。GLP-1 receptor agonists are now used for the treatment of type 2 diabetes and obesity.回顾总结走着，从找到GLP-1是胰高血糖素原经酶促裂解后引起的，再到Exendent-4 的找到。Looking back, GLP-1 was found to be a cleavage product of proglucagon processing.Exendent-4 是GLP-1发展方向世上的一种重要性的强化。Exendent-4就是种对GLP-1多巴胺肾上腺素受体拥有着急效用但能反击DPP-4光降解的肽。司美格鲁肽是世界各国面世口服药的GLP-1多巴胺肾上腺素受体着急剂。A key breakthrough came from the discovery of exendent-4. Exendent-4 is a peptide with agonistic properties at the GLP-1 receptor but resistance to degradation by DPP-4.Semiglutide, the first oral GLP-1 receptor agonist marked the next milestone.

美迪西“GLP-1”新药研发服务平台

美迪西内分泌及代谢性疾病模型