胰高血糖素样肽-1(GLP-1)是种由30或35个氨基组成的的肽雌激素,GLP-1在人体本身内以GLP-1(7-36)和GLP-1(7-37)四种抗逆性行式都存在。Glucagon-like peptide-1(GLP-1)is a 30- or 31-amino-cacid-long peptide hormone.GLP-1 exists in two equally bioactive forms,GLP-1 (7-37 )amide and GLP-1 (7-36) amide.GLP-1也是种肠促胰岛素,由胰高血糖素原基因组编号自动合成,包括由消化道 L 細胞引起,有的也可由后脑中枢神经元引起。GLP-1 is a biological product derived from the post-translational processing of proglucagon,GLP-1 is secreted by the enteroentocrine L cells,but also by some neuronal populations in the hindbrain.GLP-1可改善胰岛素发出并减轻胰高血糖素氧浓度。GLP-1 potentiates insulin release and reduces glucagon's concentration in physiological conditions.