KRAS蛋清质富含4个设备构造域。KRAS蛋清质由6条β-伸缩链和5条-螺旋运动设备构造组合而成，建立多个包括设备构造域：G设备构造域和PC版设备构造域。KRAS protein contains 4 domains.KRAS protein is made up of 6 beta-strands and 5 alpha-helicies, which form two major domains:
G-domain and C-terminal.KRAS的G构造域由残基1-166主成，包涵GTP结合在一起口袋怪兽火红，所在区域域相对于中上游定律物和GTPase解锁蛋清间的主动间能力至关必要。The G-domain of KRAS, comprised of residues 1-166, includes the GTP-binding pocket, a region within which is essential for the interactions between the putative downstream effectors and GTPase-activating proteins.G结构设计域是位置传统的，包涵进行GTP-GTP互转的switch Ⅰ和switch Ⅱ位置。The G domain is highly conserved and contains switch Ⅰ and switch Ⅱ loops, which are responsible for GDP-GTP exchange.电脑端有的是个含有CAAX基序的高变区，牵引全文翻译后修饰语并定组织细胞锚定，本区域在RAS蛋白酶的生物技术活性酶调节中起侧重于要功用。/p>The C-terminal, a hypervariable region including the CAAX motif, guides posttranslational modifications and determines plasma membrane anchoring. This region plays an important role in the regulation of the biological activity of RAS protein.
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