依据GLP-1R角色时候,GLP-1R开心剂能够分类短效和长久两个类。Based on their ability to activate GLP-1 receptor,GLP-1 receptor agonists can be classified as short- acting and long-acting GLP-1R agonist.短效GLP-1R 开心剂,必须要 月度一些并且月度俩次给药。Short-acting GLP-1R agonists are required to give either a once daily (QD) or twice-daily(BID)dosing.如艾塞那肽和利西拉肽等,长效机制GLP-1R着急剂是对化学物质分子式做出没事些结构类型突显,这个就可以不断增强其用准确时间,时候保持其用于GLP-1R 的工作能力.如杜拉鲁肽、阿必鲁肽等,每周7天给药第一次才可以。For example Exenatide and Lixisenatide, long acting GLP-1R agonists have undergone some structural modifications to enhance their duration of action while retaining their ability to act on the GLP-1 receptors. For example Albiglutide,Dulaglutide, once weekly.